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bm_sim_fit [2020/06/15 11:53] (current)
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 +====== Bloch-McConnell Simulation & Fit ======
 +{{ :bm.png?direct&250|}}
 +
 +Here you find a Bloch-McConnell simulation introduced in the publications 
 +  * **Schmitt et al. (2011), MRM 65: 1620–1629. [[http://onlinelibrary.wiley.com/doi/10.1002/mrm.22750/full|DOI: 10.1002/mrm.22750]]**, 
 +  * **Roeloffs et al. (2014), NMR Biomed., 28, 40–53 [[http://onlinelibrary.wiley.com/doi/10.1002/nbm.3192/full|doi: 10.1002/nbm.3192]]**
 +  * **Zaiss et al. (2014), NMR Biomed., 28; 217–230 [[http://onlinelibrary.wiley.com/doi/10.1002/nbm.3237/abstract|doi: 10.1002/nbm.3237]]**, 
 +  * **Meissner et al. (2015), NMR Biomed., 28, 1196–1208. [[http://onlinelibrary.wiley.com/doi/10.1002/nbm.3362/abstract|doi: 10.1002/nbm.3362]]**, 
 +It was initially based on the code provided by Shanrong Zhang published in [[http://onlinelibrary.wiley.com/doi/10.1002/mrm.20408/abstract|Woessner, Zhang, Merritt and Sherry: Numerical solution of the Bloch equations provides insights into the optimum design of PARACEST agents for MRI, MRM 2005]]. It was extended for multiple pools, including semi-solid MT, and also extended for pulsed RF saturation.
 + 
 +Dowload zipped Matlab implementations [[https://github.com/cest-sources/BM_sim_fit/archive/master.zip|here]] or find the package on [[https://github.com/cest-sources/BM_sim_fit/]]
 +
 +======  Tutorial ======
 +
 +
 +===== Bloch McConnell simulation multi-Z-spectra fit =====
 +{{youtube>O_DChxR023s?500x360|Tutorial: BM sim fit}}
 +
 +
 +This code allows for simulation of BM system upon RF presaturation 
 +  * multiple pools possible (water, 5 CEST, 1  semisolid MT)
 +  * trains RF pulses with arbitratry pulse shapes possible (gauss, sinc, spin-lock already implemented)
 +  * both analytical (if possible) and full numerical simulation possible
 +  * transient and steady-state possible
 +  * first order readout schemes possible
 +  * Both full Z-spectra and single offset evaluation possible
 +  * Ready for multi parameter simulations
 + 
 +**Read more about usage on github in
 +[[https://github.com/cest-sources/BM_sim_fit/|BM_Documentation.docx and BM_tutorial.pptx]]**
 +
 +=====Acknowledgments=====
 +This code was created by Moritz Zaiss based on the cw BM simulation and fit code of Shanrong Zhang. A revised version was created with the help of Patrick Schuenke, Christian Meyer, Christian David and Volkert Roeloffs.
 +
 +
 +
 +{{ :wordmark-full.png?direct&180|powered by GLINT}}
  
bm_sim_fit.txt · Last modified: 2020/06/15 11:53 (external edit)